Our new Obvious+ tissue clearing approach is the only process that delipidates samples without any change in morphology and with negligible effect on structural integrity.

Megatome can be a vibrating microtome created to segment a wide array of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome permits large-throughput tissue sectioning with uniform surface profile, together with minimum tissue damage and data loss.

Antibodies may possibly acquire weeks to diffuse by way of only some millimeters of tissue, having a steep labeling gradient from surface area to Main.

Megatome is designed for accuracy: the blade vibrates at a better frequency and bigger amplitude vary than other microtomes, and encompasses a one of a kind deflection Command system.

SE utilizes a rotational electric field to disperse really electromobile molecules (which include antibodies or surfactant micelles) in the course of a porous sample with no detrimental electrically charged structures within the tissue. This enables two-four day clearing of intact organs,

Our preformulated megatomi.com EasyIndex Resolution raises and homogenize the refractive index of delipidated tissue samples, rendering them completely transparent. This enables light-weight penetration in the sample and assures the acquisition of higher-resolution, in-concentrate image details.

Megatome is actually a novel microtome that allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with nominal tissue destruction and knowledge reduction.

eFLASH is a swift tissue labeling approach that allows for uniform complete-organ staining in 20 rounds of labeling.

The SmartSPIM gentle sheet microscope offers unparalleled resolution and acquisition velocity all through intact tissue volumes, when its modular design and style helps you to improve and customise personal factors.

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Leverage the Crystal clear+ tissue clearing approach, together with eFLASH and patented stochastic electrotransport systems, to speedily distinct and label full organs. Vital highlights and features incorporate:

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